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InChiKey: RMAMGGNACJHXHO-UHFFFAOYSA-N
Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel
and pS6 in all the cell lines
pre-treatment of the cells with the PI3K inhibitors
In order to examine the role of PKC in p38MAPK phosphorylation
GW9508 - selective FFA1 GPR40 agonist. CAS# 885101-89-3 P50469 InChiKey: RMAMGGNACJHXHO-UHFFFAOYSA-NGW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7. 32, 100 fold selective against GPR120, stimulates insulin secretion in a glucose sensitive manner. Product information CAS Number: 885101 89 3 Molecular Weight: 347. 41 Formula: C22H21NO3 Chemical Name: 3 (4 ((3 phenoxybenzyl)amino)phenyl)propanoic acid Smiles: OC(=O)CCC1C=CC(=CC=1)NCC1=CC(=CC=C1)OC1C=CC=CC=1 InChiKey: DGENZVKCTGIDRZ UHFFFAOYSA N InChi: InChI=1S C22H21NO3 c24
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